1-[(E)-{4-[(E)-(2,5-dimethylphenyl)diazenyl]-2,5-dimethylphenyl}diazenyl]naphthalen-2-ol
Oil Red O
CAS: 1320-06-5
Molecular Formula: C26H24N4O
1-[(E)-{4-[(E)-(2,5-dimethylphenyl)diazenyl]-2,5-dimethylphenyl}diazenyl]naphthalen-2-ol - Names and Identifiers
| Name | Oil Red O |
| Synonyms | CI 26125 Oil red O Oil Red O C.I. 26125 FAT RED 5B CI NO 26125 Oil red 3012 CERES RED 5B Solvent Red 27 Transparent Red 5B C.I. Solvent Red 27 oil red O electrophoresis 1-([4-(XYLYLAZO)XYLYL]AZO)-2-NAPHTHOL 1-[[4-[(dimethylphenyl)azo]dimethylphenyl]azo]-2-naphthol 1-[2,5-DIMETHYL-4-(2,5-DIMETHYLPHENYLAZO)PHENYLAZO]-2-NAPHTHOL 1-[(E)-{4-[(E)-(2,5-dimethylphenyl)diazenyl]-2,5-dimethylphenyl}diazenyl]naphthalen-2-ol 1-({4-[(E)-(2,5-dimethylphenyl)diazenyl]-2,5-dimethylphenyl}hydrazono)naphthalen-2(1H)-one (1Z)-1-({4-[(E)-(2,5-dimethylphenyl)diazenyl]-2,5-dimethylphenyl}hydrazono)naphthalen-2(1H)-one |
| CAS | 1320-06-5 |
| EINECS | 215-295-3 |
| InChI | InChI=1/C26H24N4O/c1-16-9-10-17(2)22(13-16)27-28-23-14-19(4)24(15-18(23)3)29-30-26-21-8-6-5-7-20(21)11-12-25(26)31/h5-15,31H,1-4H3/b28-27+,30-29+ |
1-[(E)-{4-[(E)-(2,5-dimethylphenyl)diazenyl]-2,5-dimethylphenyl}diazenyl]naphthalen-2-ol - Physico-chemical Properties
| Molecular Formula | C26H24N4O |
| Molar Mass | 408.49 |
| Density | 1.16g/cm3 |
| Melting Point | 120°C (dec.)(lit.) |
| Boling Point | 638.8°C at 760 mmHg |
| Flash Point | 103℃ |
| Water Solubility | Soluble in ethanol:chloroform (1:1). Insoluble in water. |
| Solubility | Soluble in benzene, soluble in chloroform, glacial acetic acid, ether, ethanol, acetone, petroleum ether, non-volatile oil, hot glycerin and volatile oil |
| Vapor Presure | 6.46E-17mmHg at 25°C |
| Appearance | Dark brown powder or red powder |
| Color | Red to dark greenish-brown |
| Maximum wavelength(λmax) | ['518 nm, 359 nm'] |
| BRN | 3491382 |
| Storage Condition | room temp |
| Refractive Index | 1.631 |
| MDL | MFCD00003898 |
| Use | This product is for scientific research only and shall not be used for other purposes. |
1-[(E)-{4-[(E)-(2,5-dimethylphenyl)diazenyl]-2,5-dimethylphenyl}diazenyl]naphthalen-2-ol - Risk and Safety
| Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin. R67 - Vapors may cause drowsiness and dizziness R36 - Irritating to the eyes R11 - Highly Flammable |
| Safety Description | S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S16 - Keep away from sources of ignition. S7 - Keep container tightly closed. |
| UN IDs | UN1219 - class 3 - PG 2 - Isopropanol, solution |
| WGK Germany | 3 |
| TSCA | Yes |
| HS Code | 32041900 |
1-[(E)-{4-[(E)-(2,5-dimethylphenyl)diazenyl]-2,5-dimethylphenyl}diazenyl]naphthalen-2-ol - Reference
| Reference Show more | 1. Huang Zhuang, Li Jing, Du Hongzhi, et al. Lipid-lowering Effect of Panax notoginseng Alcohol Extract on Caenorhabditis elegans [J]. World Science and Technology-Modernization of Traditional Chinese Medicine 20202022 Volume 5 Page 1648-1653 ISTIC PKU CSCD 2020. 2. Qi Fangfei, Lou Bin, Yang Qing. Establishment and Comparison of Rat and Human Macrophage-Deriving Foam Cell Models [J]. Fudan Journal (Medical Edition), 2019, 46(004):445-453. 3. Zhang Lei, Hao Jingwei, Wan Chunlei, et al. Optimization of Extraction Process of Polysaccharide from Inonotus obliquus and Its Effect on Fat Accumulation of Human Hepatoma Cell HepG2 [J]. Jiangsu Agricultural Sciences, 2019, 047(010):201-204. 4. Zhong, Ximing, et al. "Bio-based coatings with liquid repellency for various applications." Chemical Engineering Journal 382 (2020): 123042.https://doi.org/10.1016/j.cej. 2019.123042 5. Duan, Lian, et al. "Magnetic Targeting of HU-MSCs in the Treatment of Glucocorticoid-Associated Osteonecrosis of the Femoral Head Through Akt/Bcl2/Bad/Caspase-3 Pathway." International journal of nanomedicine 15 (2020): 3605.https://dx.doi.org/10.2147/IJ 6. [IF=9.229] Ximing Zhong et al."Robust Hyperbranched Polyester-Based Anti-Smudge Coatings for Self-Cleaning, Anti-Graffiti, and Chemical Shielding."Acs Appl Mater Inter. 2019;11(15):14305-14312 7. [IF=13.273] Ximing Zhong et al."Bio-based coatings with liquid repellency for various applications."Chem Eng J. 2020 Feb;382:123042 8. [IF=7.446] Linling Gan et al."Tetrazanbigen Derivatives as Peroxisome Proliferator-Activated Receptor Gamma (PPARγ) Partial Agonists: Design, Synthesis, Structure-Activity Relationship, and Anticancer Activities."J Med Chem. 2021;64(2):1018-1036 9. [IF=6.4] Meichen Liu et al."Fe3O4@Polydopamine-Labeled MSCs Targeting the Spinal Cord to Treat Neuropathic Pain Under the Guidance of a Magnetic Field."Int J Nanomed. 2021; 16: 3275-3292 10. [IF=5.81] Lai Jianfei et al."Activation of AMP-Activated Protein Kinase-Sirtuin 1 Pathway Contributes to Salvianolic Acid A- Induced Browning of White Adipose Tissue in High-Fat Diet Fed Male Mice."Front Pharmacol. 2021 May;0:1361 11. [IF=5.279] Xiaoying Zhang et al."Mechanism of Pentagalloyl Glucose in Alleviating Fat Accumulation in Caenorhabditis elegans."J Agr Food Chem. 2019;67(51):14110-14120 12. [IF=5.161] Ximing Zhong et al."Preparation of water-borne non-fluorinated anti-smudge surfaces and their applications."Prog Org Coat. 2020 May;142:105581 13. [IF=5.115] Lian Duan et al."Magnetic Targeting of HU-MSCs in the Treatment of Glucocorticoid-Associated Osteonecrosis of the Femoral Head Through Akt/Bcl2/Bad/Caspase-3 Pathway."Int J Nanomed. 2020; 15: 3605-3620 14. [IF=4.225] Huang Xian-ju et al."Veratrilla baillonii Franch Could Alleviate Lipid Accumulation in LO2 Cells by Regulating Oxidative, Inflammatory, and Lipid Metabolic Signaling Pathways."Front Pharmacol. 2020 Sep;0:1511 15. [IF=3.765] Hu Xuelian et al."TNBG-5602, a novel derivative of quinoxaline, inhibits liver cancer growth via upregulating peroxisome proliferator-activated receptor γ in vitro and in vivo."J Pharm Pharmacol. 2019 Oct;71(11):1684-1694 16. [IF=4.009] Zixuan Wang et al."An animal study on the effect of topically administered ambroxol for dry eye."Front Biosci-Landmrk. 2022 Jan 5;27(1):4 17. [IF=13.281] Ziyu Wu et al."Multi-Pathway Microenvironment Regulation for Atherosclerosis Therapy Based on Beta-Cyclodextrin/L-Arginine/Au Nanomotors with Dual-Mode Propulsion."Small. 2021 Dec 16 18. [IF=17.782] Chen Xixi et al."Lipid droplets as endogenous intracellular microlenses."Light-Sci Appl. 2021 Dec;10(1):1-11 19. [IF=4.367] Linghan Deng et al."Dehydrofluorination and one-pot hydrothermal process for polyvinylidene fluoride/polytetrafluoroethylene@TiO2 membranes with durable superhydrophobicity toward repeatable separating and photodegrading oily dyes in water-in-oil emulsions |
1-[(E)-{4-[(E)-(2,5-dimethylphenyl)diazenyl]-2,5-dimethylphenyl}diazenyl]naphthalen-2-ol - Introduction
Biological stain; Lipid and fat staining in starch gel electrophoresis; Used as fat stain in microscopic technology.
Last Update：2022-10-16 17:13:24
1-[(E)-{4-[(E)-(2,5-dimethylphenyl)diazenyl]-2,5-dimethylphenyl}diazenyl]naphthalen-2-ol - Reference Information
| color index | 26125 |
| biological applications | Detecting early pages of atherosclerotic lesion formation; treating obesity,hyperlipidemia,fatty liver,leptin production disorders; Dental impression material; measuring phagocytosis |
| EPA chemical information | Information provided by: ofmpub.epa.gov (external link) |
| introduction | solvent red 27 is also called oil red o. as a commonly used antioxidant, it has the function of colorant. Solvent Red 27 can distinguish fuel without adding antioxidants, and can also reduce carbon deposits in the combustion chamber. Solvent Red 27 Due to the presence of methyl groups in the molecule, the above oxidation reaction is accelerated and is beneficial to the solubility in fuel. |
| uses | solvent red 27 has many uses: 1. it is used for coloring various oils, transparent paints, floor wax and plexiglass. 2. Biochemical research. Biological stain; Lipid and fat staining in starch gel electrophoresis; Used as fat stain in microscopic technology. 3. Biological stain, lipid and lipoprotein staining in starch gel electrophoresis. Used as a fat stain in microscopy. Red O stain is suitable as a lipid/lipoprotein stain for cellulose acetate. |
| application | solvent red 27, also known as oil red o, can be used as biological stain in biochemical research. Lipid and fat staining in starch gel electrophoresis; Used as fat stain in microscopic technology. |
| preparation | 1, 2,4-dimethylaniline diazotization 1 part 2,4-dimethylaniline mixed with 2.1-2.5 parts hydrochloric acid, under stirring to completely dissolve, cooling to 3-10 ℃, adding 1.1-1.2 parts of sodium nitrite, PH ≤ 2, for about 1 hour. Diazo to be coupled. 1 part of 2,2, 5-dimethylaniline is dissolved in 0.9-1.1 parts of hydrochloric acid, and the temperature is controlled to be 15-30 ℃. PH = 4-5 range. Gradually add the prepared diazonium salt and keep it for 4-6 hours. Heat up to 30-60 ℃. After 0.5-1.0 hours of heat preservation, cool to room temperature and filter. Determine the filtration and solid content, estimate the amount of coupling products, as the basis for the second diazotization and coupling. 3. Take the above filter for the second diazotization, add water to paddle, add 2 parts hydrochloric acid to stir, cool to 12-20 ℃, add 1 part sodium nitrite, keep for 2 hours, and prepare for the second coupling. 4. One part of ethylnaphthol or calculated according to the amount of coupling product in step 2, add 1.5-1.6 parts of caustic soda, raise the temperature to 60 ℃ to dissolve, cool the temperature to 20 ℃, add the second diazonium salt within 1 hour, have a PH end point of 7, keep the temperature for 1 hour, raise the temperature to 90 ℃, keep the temperature for 1 hour, and filter while hot. 5. Filter and wash with water until 1% silver nitrate solution is similar to tap water. Filter and dry at 70-80 ℃, grind to 60-100 mesh, and pack solvent red 27. |
Last Update：2024-04-09 21:01:54
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Product Name: Oil red O Visit Supplier Webpage Request for quotationCAS: 1320-06-5
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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